Custom Synthesis

Custom Quote Request

The AccuStandard Synthesis Department employs several PhD Organic Chemists with many years of pertinent academic and industrial experience. The experienced staff has developed hundreds of pure chemical compounds for companies and governmental agencies around the world. The well-equipped laboratory has made many notable synthesis projects possible. AccuStandard specializes in synthesizing chemicals of high purity to be used as reference standards. Our custom synthesis capabilities range from milligram to kilogram scale.

Analytical Capabilities




• access to additional analytical instrumentation possible if necessary

Synthesis and Purification

• Milligram to Kilogram Glassware

• Inert Conditions Equipment

• Microwave Synthesis System

• High Performance Flash Chromatography

• Distillation Equipment – High Vacuum Distillation, Molecular Distillation (Kugelrohr), and Spinning Band Columns

• Parr Pressure and Hydrogenation Reactor

AccuStandard is renowned for its quick response to customer requests for new compounds and its partnership in developing new methods. For example, the offering of a wide variety of nonyl- and octylphenol ethoxylate derivatives led to the development of ASTM methods D7065-06 and D7485. The company’s Synthesis Department implements the design and manufacture of important and unique products. Significant pioneering achievements include the synthesis of all 209 PCB congeners and all of the 209 PBDE (polybrominated diphenyl ethers) congeners. Among the more recent introductions are the hydroxy and methoxy PBDE congeners and mixed bromo/chloro hydroxy and methoxy diphenyl ethers. The syntheses of pesticides, PCBs, PBDEs, PAHs, explosives and other organic pollutants, as well as their metabolites, are an integral part of the department’s efforts. Fluorinated PBDEs, synthesized in our lab, have been used to substitute the expensive isotopically labelled PBDE surrogates. Also, synthesis of the complete set of ethanesulfonic acid (ESA) and oxanilic acid (OA) pesticide derivatives has resulted in the addition of reference standards for EPA method 535.

AccuStandard’s Custom Synthesized Products

• PCBs (all 209 congeners), & hydroxy, methoxy, and methylsulfonyl metabolites

• Chloro- and bromodibenzodioxins and furans

• PBDEs (all 209 congeners) & hydroxy, methoxy, and chloro metabolites

• Fluorinated PBDEs

• Alpha-, beta- and gamma-hexabromocyclododecane (HBCD)

• Other Brominated Flame Retardants

• PBBs

• PAHs, nitro-PAHs, methyl-PAHs

• Pesticides and metabolites

• Explosives and metabolites

• Nonyl- and octylphenol ethoxylates

• Mono- and di-phthalate esters

• Organophosphates

• Other rare chemical